After Homer accidentally pollutes the town’s water supply, Springfield is encased in a gigantic dome by the EPA and the Simpsons are declared fugitives.

When Flanders’ parents prove to prefer Homer’s company to his, he jealously responds by giving Homer a shiner, and then tries desperately to reconcile with him. Meanwhile, Lisa is at…

Lisa’s school project leads to the discovery of a new drug that makes the elderly less cranky and more tolerable.

During a research trip, Lisa learns that Sideshow Bob is the chief scientist at a big chemical engineering company; Marge tries to teach a teen church group about healthy sexual…