A chronicle of the 20th century trans experience, bookended by the 1966 Compton Cafeteria riots in San Francisco.

Sara, Kreizler and Moore travel to Brooklyn in search of clues. Byrnes plans to double-cross the team as the killer’s behavior becomes unhinged. Sara and Moore’s feelings for each other…

The ER quickly fills up after a heavy storm causes a devastating helicopter crash. Conrad, Devon and the rest of the Chastain doctors rush to treat patients including the helicopter…

Mac and Desi travel with Bozer to his childhood home when his aunt dies in a tragic accident, however, they soon discover she may have been murdered for trying to…

When Mac and Riley go missing and wake up 24 hours later in a corn field with no memory of how they got there, they must unravel the mystery to…

Mac and Riley head overseas together to prevent a governmental collapse and inadvertently inhale new deadly microscopic technology.

Mac, Desi and Russ go undercover during a royal Indian wedding to protect a princess whose policies could put her life in danger. Also, Russ and Sophia come face-to-face at…

Caroline has news to share, forcing Dr. Charles to make a serious decision about their relationship. Maggie meets her sister’s new boyfriend, but discovers danger may lie ahead. Dr. Rhodes…

Dr. Manning and Jeff Clarke are forced to figure out a mystery illness when an Indonesian man who doesn’t speak English arrives at the hospital in dire straights. Maggie takes…

A new job forces Will to take a hard look at the choices he’s made. Rachel must come to terms with the fact her family home has finally been sold….