As she and her friends try to make time for each other no matter what, Issa looks back on all it took to get to where she is today.

After facing numerous obstacles, Issa gets discouraged about her project, while Molly helps give Issa a drama-free 30th birthday.

Still adjusting to newfound responsibilities, one of Issa’s exes finds himself torn between two places, while an important woman in his life remains wary of his ability to be fully…

Tensions escalate between Scottie and Howard forcing Tom to reach out to an unexpected ally for help. As explosive family secrets come to light, Tom races against time to learn…

A tip throws the case into jeopardy. Secrets surface from Axe’s past.

Senior and Chuck’s friends take Chuck on a retreat to regroup. Prince looks to consolidate his wins. Wendy tries to figure out Prince’s bigger picture. Sacker reckons with some old…

Axe’s latest move takes him back to his roots but puts him in Mike Prince’s line of fire. Chuck steps into a new role and meets an intriguing colleague. Taylor…

Jeanie asks Greg to help Al get into a special AIDS-program at the hospital. Olbes brings in her grandfather, who had a stroke.

Benton tries to find out if everything’s OK with Carla’s baby. Carter tries to get a man operated, despite the fact Anspaugh thinks he will die no matter what.

Benton can’t keep his mind on the job, Mark and Chuny break up and Carol does what she needs to do regarding the fatal error she has made.

Doug treats a dying 17-year old cystic fibrosis patient who doesn’t want to be resuscitated. Carter gets to operate Benton.

Carol will hear whether her suspension is permanent or not. Mark and Doyle do what they can to get a patient with Down syndrome on a heart transplant list.

Carter feels guilty about Gant’s death. Benton doesn’t want to talk about it.

House has to defend himself when he treats a patient who has legally chosen to refuse treatment.

Family troubles: Jack with his brother and father while Morris worries about his own brother.

While Jack has problems with Curtis, CTU discovers a nuclear threat and raids a terrorist warehouse, and a shocking explosion shakes LA.

Four more “suitcase nukes” are out there, and Jack’s only lead takes him to the home of his brother.

Jack finds himself confronting his father while the lead terrorist needs help if he’s to explode the remaining bombs.