Dr. Shaun Murphy, a young surgeon with autism and savant syndrome, relocates from a quiet country life to join the prestigious St. Bonaventure hospital’s surgical unit. Alone in the world…

The CSI team investigates a fire at a music venue that leaves four people dead, including two band members.

The doctors of Grey Sloan Memorial Hospital are forced to put their emotions aside when a catastrophic event occurs.

As the doctors continue to tackle an unfathomable crisis, they are reminded of what is important and are brought closer together.