Clark and Lois disagree on the best way to figure out if Ally Allston went to the Inverse World. Meanwhile, John Henry makes a surprising discovery and Lois sets out…

Chrissy Beppo, with the authorization of the Department of Defense, has a message for the people of Smallville, not only is the merging of planets real, it is happening.

Lois, Clark, and Natalie notice a difference in John Henry’s behavior and fear something might be very wrong. Meanwhile, Kyle encounters an awkward moment with Lana while stopping by the…

Lois and Chrissy are on a mission to find Lois’ sister Lucy and Jonathan and Jordan become more and more unsettled as Clark’s painful visions continue. Meanwhile, Lana, Kyle and…

Lois tells Clark that she and Chrissy plan to do a deeper dive into the Inverse Society and Lana and Sarah try to comfort each other after the fallout at…

Lois and Chrissy pursue a new lead in the Mannheim investigation against Clark’s wishes. Meanwhile, Jonathan, Jordan, and Nat face an unexpected obstacle.

Adam and Andi are shocked when they finally meet Lowell’s wife, Jen.

Adam attempts to organize a birthday dinner for Andi and he discovers that managing guests isn’t easy.

Chastain picks up the pieces after the fall out with the corrupt medical device company Quovadis, leaving Marshall ready to charter new territory in the medical field, and Devon to…

Devon’s doubts about his relationship reach a peak as his friends and family gather for his big wedding day. As Chastain’s leading medical device company, Quovadis, continues to succeed, Julian…

When patients from the hospital’s prescription drug trial start suffering life threatening side effects, Nic fears that her sister Jessie may be in danger. As a result, she and Conrad…

Conrad goes head-to-head with Bell after he recommends one of Julian’s risky medical devices to Zoey, who’s already lost one son and is back in the hospital with the other….

Nic and Conrad contemplate their past when they team up to diagnose a happy husband and wife who are both admitted to the hospital with mysterious symptoms. Bell and Marshall…

Chastain is flooded with concert goers when a stampede at a music festival grounds leaves many in need of doctors. As Conrad and Nic race to help Josh Robinson, a…

When Bell makes the executive call to utilize Julian Booth’s medical devices, rather than the hospital’s usual products, Kit and AJ must stop their momentary feuding in order to team…

Bell grows frustrated when Marshall Winthrop, Conrad’s dad and new chairman of the board, requests Conrad’s input in his discussions about the hospital’s expenses. As Conrad and Nic work to…

Supergirl does battle with the deadly Master Jailer, who is hunting and executing escaped Fort Rozz prisoners. Also, Cat hires a second assistant, Siobhan Smythe, who immediately tries to one-up…

Kara travels to Superman’s Fortress of Solitude in hopes of learning how to defeat Indigo, a dangerous being who can transport via the Internet and who has a connection to…

Kara turns on her friends and the citizens of National City after being exposed to Red Kryptonite makes her malicious and dangerous. Also, Cat appears on THE TALK to discuss…

J’onn J’onzz reveals the details of meeting Kara and Alex’s father, Dr. Jeremiah Danvers, and assuming Hank Henshaw’s identity. Also, Kara debates trusting someone new with her secret identity and…

Kara gains a new ally when the lightning-fast superhero The Flash suddenly appears from an alternate universe and helps Kara battle Siobhan, aka Silver Banshee, and Livewire in exchange for…

Kara must find a way to free her friends when Non and Indigo use mind control to turn National City’s citizens into their own army.

Supergirl is forced to do battle with an unexpected foe and must risk everything – including her life – to prevent Non and Indigo from destroying every person on the…

Supergirl’s powers are tested when Reactron, one of Superman’s formidable enemies, arrives in National City and targets the young hero. Also, Cat plans to run an exposé on Supergirl.

Kara’s Thanksgiving may be ruined when she suspects her foster mother, Dr. Danvers, who is coming to town, disapproves of her new role as a superhero. Also, when an accident…

Kara’s two identities are stretched thin when Supergirl must protect National City from a series of bombings and Kara is tasked with babysitting Cat’s son, Carter. Also, James is conflicted…

Personal and professional stress get the better of Kara when she goes too far during a training exercise against Red Tornado, a military cyborg commissioned by Lucy Lane’s father, General…

Kara goes toe-to-toe with Astra when her aunt challenges Kara’s beliefs about her mother. Also, Cat is threatened with being removed as the CEO of CatCo after a hacker exposes…

Kara does her best to support Winn when his father, the supervillain Toyman, breaks out of prison and seeks out his son for unknown reasons. Also, Cat offers Lucy a…

Kara must help Hank face his painful past when a White Martian, a member of the alien race that wiped out his people, kidnaps Senator Miranda Crane, an anti-alien politician….

Kara faces off against her mirror image when Bizarro, a twisted version of Supergirl, sets out to destroy her. Also, Kara grows closer with Cat’s son, Adam.

Johnny sets out to complete his father’s work; Lana leads the charge to finally shut down Briarcliff.

An exorcist is called to Briarcliff to help save a troubled farm boy; Sister Jude’s darkest secret is revealed.

A violent storm allows a group of patients to plan a daring escape; Sister Jude is haunted by her past.

A mysterious little girl is abandoned at Briarcliff; the Monsignor makes a Faustian pact with Dr. Arden; the origin of Bloody Face is revealed.

The Monsignor takes an unlikely convert under his wing; Lana secures a new piece of evidence that can exonerate Kit; Dr. Arden witnesses a miraculous return.

Terrifying evils blur the boundaries between reality and insanity at the Briarcliff Manor.