In Rat Pack-era Vegas, the team is hot on Flynn’s heels with the era’s most infamous mistress in toe.

A series of gruesome murders leads Nick and Kate to suspect that Jack the Ripper has returned from the grave… and is stalking victims in Chicago.

Castriel investigates the mass slaughter of angels and finds a lone survivor… and an old friend. Meanwhile, Sam and Dean capture Gadreel, and Metatron begins the ending of his story.

Sam and Dean investigate a brutal death and discover that the killer is a lycanthrope: a werewolf.

Major Carter joins an alien pilot for a space race, where the winner is awarded a lucrative contract with the planet’s most powerful corporation. But the rest of the team…