Just when the ER is understaffed and swamped, two children who were brought in turn out to have full blown smallpox. The entire ER must be locked down. The staff…

Dr. Carter, Abby and other staff of the ER are quarantined as the CDC investigate a mysterious, deadly outbreak.

With the intention of helping his parolee get a loan, Henry, along with Paige, go to a bank but instead the parolee decides to take everyone at the bank hostage….