After Cottonmouth and Scarfe’s bloody clash, Luke realizes that saving the community may turn former allies into enemies, and enemies into allies.

A cataclysmic event leaves the doctors shaken; Callie, on the verge of a life-changing moment, starts imagining about the hospital and her friends.

Personal and work pressures are adding up and have Meredith visibly on edge, Owen conducts formal interviews for the Chief Resident position, Cristina grows increasingly defiant, Alex and Lucy’s undefined…

News of Meredith’s dishonesty in the clinical trial comes to light, leading to unanticipated consequences for her and others; Cristina finds herself in a compromising situation, which forces her to…

Derek breaks ground on his Alzheimer’s clinical trial and Meredith can’t help but feel left out; Bailey’s attempt to take the hospital into the age of new media with live…

Thatcher Grey, Meredith and Lexie’s father, returns to Seattle Grace with stomach pains and a new, twenty-something tattooed girlfriend, Danielle. Meanwhile, Alex clashes with the new OB, Dr. Lucy Fields,…

Meredith, looking to prove she is Chief Resident material, learns that anything and everything can happen in an hour’s time when she steps up to run the ER for a…

Meredith must choose between her fertility treatments and her eyesight when she begins having trouble seeing, Mark makes it clear to Callie and Arizona that he takes his role as…

Richard is desperate for Derek and Meredith to accept Adele into their Alzheimer’s trial, but will Adele stand in her own way? Meanwhile Mark and Arizona have conflicting ideas of…