Something unnatural is happening in the swamps outside Marais, Louisiana. When a mysterious illness strikes the town, CDC investigator (and former Marais native) Abby Arcane is sent to investigate.

Still on the run, Jennifer and Khalil succumb to their feelings for one another and begin planning their future together. Meanwhile, Jefferson approaches Henderson with a favor.

Jefferson suspects that Tobias is behind a recent malicious attack. He brings this news to Henderson but doesn’t get the answer he was looking for. Meanwhile, Lynn is confronted by…

When Anissa returns to work at the clinic, she meets a domestic violence victim who motivates her to take action. Meanwhile, Gambi makes a discovery.

After Jennifer and Khalil escape, they take refuge in a barn and Jennifer desperately tries to save a now feverish Khalil, who has grown worse from Cutter’s poisonous blade. Meanwhile,…

Gamby and Russell eye a homecoming football game as a way to further break Dr. Brown’s spirit.

Gamby bonds with Amanda during teacher workday; Russell’s patience is tested; Dr. Brown deals with the sudden appearance of her ex-husband, Dascious.

Gamby and Russell look to finish what they started; Gamby confronts Amanda about her relationship with Hayden.

Recovering from his wounds, Gamby returns to a dramatically changed North Jackson High.