1882. After the death of her father and accompanied by Peggy Scott, Marian Brook travels to New York to live with her aristocratic aunts, Agnes van Rhijn and Ada Brook….

A pickpocket dies of anthrax poisoning, putting Holmes and Watson on the trail of the toxin’s source in order to prevent more deaths.

When Reddington takes Liz to the mysterious epicenter of his empire, their shared past reveals itself and long buried secrets are divulged.

Red directs the task force to investigate Roanoke, a legendary criminal who orchestrates elaborate extractions. Meanwhile, Liz works to hatch a secret plan with her mother, Katarina Rostova.

As Liz pushes a source for answers, Red and the task force grapple with the implications of her actions. Tensions boil over and a drastic action is taken, which will…

The team suspects the latest number to be a potential stalker/ killer. Root plots her escape from the institution and gives her psychiatrist a big surprise.